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Athletes and Ozempic: What You Need to Know

Updated: 6 days ago

The truth about GLP-1 weight loss medications and performance.


Content provided by Eden Morris, MS, RD, CIEC

Check out Eden's website, instagram, and podcast


Spoon with pills in it

What are GLP-1 medications?

GLP-1 stands for glucagon-like peptide-1.


Glucagon-like peptide-1 (GLP-1) receptor agonists, also known as GLP-1 agonists, GLP-IRAs, GLP-1 analogs, or incretin mimetics, are a class of medications that activate the GLP-1 receptor, leading to reduced blood sugar levels and decreased appetite, which in turn results in lower energy intake.


GLP-1 agonists

  • Mimic a gut hormone that slows digestion

  • Suppress appetite

  • Help manage blood sugar

  • These medications were originally developed for diabetes—now the doses are being maximized to market them for intentional weight loss.


Why this topic matters.

GLP-1 medications, such as Ozempic and Wegovy, are increasingly prevalent, even in sports. But these drugs can seriously impact fueling, performance, and recovery. Some professional athletes have been promoting or openly using GLP-1s, which can create mixed messages for younger athletes and fans. If you're considering these medications, make sure you fully educate yourself, consult trusted medical professionals, and understand how they may affect both your health and your athletic performance.


Why are some athletes curious about GLP-1s?

  • Pressure to stay lean

  • Weight stigma in and out of sport

  • Desire for control over food and body


The problem for athletes is that GLP-1 agonists...

  • Slow digestion can cause nausea and GI distress, suppress appetite

  • These medications make it hard to eat or absorb enough fuel for training


When fuel drops too low...

Low energy availability can lead to Relative Energy Deficiency in Sport (RED-S), which can cause:

  • Hormone disruption

  • Fatigue and injuries

  • Loss of muscle

  • Lower performance


How athletic performance takes a hit

  • Slower recovery

  • Poor muscle repair

  • Blunted training adaptation

  • Your body cannot perform efficiently when it's running on empty


And the effects are not just physical, GLP-1s quiet "food noise", but can also:

  • Dull hunger and fullness cues

  • Reduce the enjoyment of eating

  • Increase disconnection from your body


Before considering GLP-1s, ask yourself:

  • Am I eating enough to match the energy demands of training?

  • Are my goals about weight or performance?

  • Have I explored ways to improve my body image and fueling strategies?

  • Am I working with a sports dietitian who can give me more information about these medications?





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